7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate

Tlhaloso e Khutšoanyane:

Lebitso: 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one

CAS: 160129-45-3

Bohloeki: ≥99.0% (HPLC)

Ponahalo: Botala bo Khanyang ho ea ho Phofo e Sehla e Khanyang

Bohareng ba Tolvaptan (CAS 150683-30-0) bakeng sa phekolo ea Hyponatremia

Boleng bo Phahameng, Tlhahiso ea Khoebo

Lipatlisiso: alvin@ruifuchem.com

 


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
Litlhaloso tse tšoanang 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
Nomoro ea CAS 160129-45-3
Nomoro ea KAtse RF-PI395
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C10H10ClNO
Boima ba Molek'hule 195.65
Melting Point 103.0 ho isa ho 107.0 ℃
Solubility E qhibiliha ka Methanol
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Botala bo Khanyang ho ea ho Phofo e Sehla e Khanyang
Mekhoa ea ho Itsebahatsa NMR, HPLC
Mokhoa oa Bohloeki / Analysis ≥99.0% (HPLC)
Tahlehelo ka ho Omisa ≤1.0%
Masalla a ho Ignition ≤0.50%
Tšilafalo efe kapa efe e le 'Ngoe ≤0.50%
Litšila ka Kakaretso ≤1.0%
Tekanyetso ea Teko Boemo ba Khoebo
Tšebeliso Bohareng ba Tolvaptan (CAS 150683-30-0), phekolo ea Hyponatremia

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya le mongobo.

Melemo:

1

LBH:

Kopo:

7-Chloro-1,2,3,4-tetrahydrobenzo [b]azepin-5-one (CAS 160129-45-3) ke karolo e bohareng ea motsoako oa Tolvaptan (CAS 150683-30-0).Tolvaptan ke mohanyetsi ea khethang, ea nang le tlholisano ea molomo ea nonpeptide arginine vasopressin V2 receptor antagonist e nang le IC50 ea 1.28µM bakeng sa thibelo ea AVP-induced platelet aggregation.Tolvaptan e sebelisoa ho alafa hyponatremia e amanang le ho hloleha ha pelo, ho thatafala ha sebete, le lefu la homone e sa lokelang ea antidiuretic.Tolvaptan o boetse o le litekong tse potlakileng tsa bongaka tsa lefu la liphio tsa polycystic.Kalafo e nang le Tolvaptan e baka phokotso ea boima ba 'mele ka potlako le ka nako e ts'oanang le keketseho ea tlhahiso ea moroto, e ntlafatsa le / kapa e etsa hore sodium ea serum e tloaelehe ho bakuli ba hyponatremic, e fokotsa matšoao a tšubuhlellano le ho eketsa lenyora.

  • Ngola molaetsa wa hao mona mme o re romele wona