Sofosbuvir Intermediate CAS 21382-82-1 Purity ≥98.0% (HPLC)
| Name | 2-(triphenyl-phosphanylidene)-propionic acid ethyl ester |
| Synonyms | triphenyl(1-[ethoxycarbonyl]ethylidene)phosphorane; ethyl 2-(triphenylphosphoranylidene)propanoate |
| CAS Number | 21382-82-1 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C23H23O2P |
| Molecular Weight | 362.41 |
| Brand | Ruifu Chemical |
| Item | Specifications | Results |
| Appearance | Yellow Powder | Yellow Powder |
| Purity / Analysis Method | ≥98.0% (HPLC) | 98.5% |
| Loss on Drying | ≤1.00% (60℃, 2h) | 0.39% |
| Sum of PH3P+PH3PO | ≤2.00% (HPLC) | Conforms |
| Unspecified Related Substances | ≤0.50% (HPLC) | Conforms |
| Test Standard | Enterprise Standard | Conforms |
| Application | Intermediate of Sofosbuvir (CAS: 1190307-88-0) | |
Package: Bottle, Aluminum foil bag, 25kg/Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture
Manufacturer with High Purity and Stable Quality
Commercial Supply Sofosbuvir (CAS: 1190307-88-0) and Related Intermediates:
Sofosbuvir CAS: 1190307-88-0
N4-Benzoylcytosine CAS: 26661-13-2
triphenyl(1-[ethoxycarbonyl]ethylidene)phosphorane CAS: 21382-82-1
L-Alanine Isopropyl Ester Hydrochloride CAS: 62062-65-1
Pentafluorophenol CAS: 771-61-9
N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester CAS: 1334513-02-8
Sofosbuvir is a drug used for the treatment of hepatitis C. It is recommended to be used in combination with other drugs (such as velpatasvir) for the first-line treatment for HCV genotypes 1, 2, 3, 4, 5, and 6. It takes effect through acting as a nucleotide analog inhibitor, being capable of specially inhibiting the HCV NS5B (non-structural protein 5B) RNA-dependent RNA polymerase.
