Tolvaptan CAS 150683-30-0 API Factory High Quality

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: Tolvaptan

CAS: 150683-30-0

Assay (HPLC): 98.0~102.0%

Ponahalo: Bosoeu ho isa ho Bosoeu ba Crystalline Powder

Mohanyetsi ea matla le ea khethang oa vasopressin V2 receptor

API Boleng bo Phahameng, Tlhahiso ea Khoebo

Lipatlisiso: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Phepelo ea Moetsi
Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: Tolvaptan
CAS: 150683-30-0

Lintho tsa Lik'hemik'hale:

Lebitso Tolvaptan
Lebitso la Lik'hemik'hale N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide
Nomoro ea CAS 150683-30-0
Nomoro ea KAtse RF-API101
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule Setšoantšo sa C26H25ClN2O3
Boima ba Molek'hule 448.94
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Bosoeu ho isa ho Bosoeu ba Crystalline Powder
Mekhoa ea ho Itsebahatsa IR, HPLC
Assay (HPLC) 98.0 ~ 102.0% (motheong oa anhydrous)
Melting Point 219.0~222.0℃
Tahlehelo ka ho Omisa ≤0.50%
Masalla a ho Ignition ≤0.10%
Tšilafalo e le Mong ≤0.50%
Litšila ka Kakaretso ≤1.0%
Litšepe tse boima ≤20ppm
Metsoako e setseng Kopana le Litlhophiso
Tekanyetso ea Teko Boemo ba Khoebo
Tšebeliso Mekhatlo ea Meriana

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya le mongobo.

Melemo:

1

LBH:

Kopo:

Tolvaptan (CAS 150683-30-0), eo hape e tsejoang e le OPC-41061, ke mohanyetsi ea khethang, ea nang le tlhōlisano ea arginine vasopressin receptor 2 e sebelisetsoang ho phekola hyponatremia (maemo a tlaase a sodium ea mali) a amanang le congestive heart failure, cirrhosis, le syndrome ea ho sa lokelang. Hormone ea antidiuretic (SIADH).Otsuka Pharmaceutical e nang le laesense ea tolvaptan tlas'a lebitso la khoebo la Samsca ka mor'a hore FDA e amohele moriana ona ka May 2009. Tolvaptan e boetse e bontšitse katleho khahlanong le lefu la liphio tsa polycystic.Tekong ea 2004, ho ile ha hlokomeloa hore tolvaptan e tsamaisoang ka li-diuretics tsa setso e eketsa ho ntšoa ha metsi a mangata le ho ntlafatsa boemo ba sodium maling ho bakuli ba nang le lefu la pelo ntle le ho hlahisa litlamorao tse kang hypotension (khatello e tlase ea mali) kapa hypokalemia (ho fokotseha ha maemo a potasiamo maling).Setlhare le sona se ne se sa bonts'a phello e mpe mosebetsing oa liphio.

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