(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8 Atazanavir Intermediate High Purity

Short Description:

Name: (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane

(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane

CAS: 98760-08-8

Appearance: White to Off-White Crystalline Powder

Purity: ≥99.0% (HPLC)

Intermediate of Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor

High Quality, Commercial Production

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Product Detail

Product Tags

Description:

Manufacturer Supply Atazanavir Related Intermediates
Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
High Quality, Commercial Production

Chemical Properties:

Chemical Name	(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane
Synonyms	(2R,3S)-3-(tert-Boc)amino-1,2-epoxy-4-phenylbutane; (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane; Atazanavir Intermediate; Atazanavir Impurity C; threo-N-Boc-L-phenylalanine epoxide
CAS Number	98760-08-8
CAT Number	RF-PI288
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C15H21NO3
Molecular Weight	263.34
Shipping Condition	Under Ambient Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Off-White Crystalline Powder
Identification	The identification is confirmed by HPLC RT
Solubility	Soluble in Methanol
Specific Rotation	-10°~ -20°
Water (K.F)	≤0.50%
Residue on Ignition	≤0.20%
Related Substances
Impurity (RRT0.97)	≤0.30%
Any Single Impurity	≤0.30%
Total Impurities	≤1.0%
Heavy Metals	≤20ppm
Purity / Analysis Method	≥99.0% (HPLC)
Enantiomeric Purity	≤0.30%
Test Standard	Enterprise Standard
Usage	Intermediate of Atazanavir (CAS 198904-31-3) HIV-1 Protease Inhibitor

Package & Storage:

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS 98760-08-8) with high quality, an intermediate of Atazanavir (CAS 198904-31-3) and Atazanavir Sulfate (CAS 229975-97-7). Atazanavir is a novel azapeptide HIV protease inhibitor (PI).

Atazanavir is an inhibitor of human immunodeficiency virus type 1 (HIV-1) protease, an enzyme that is essential for the processing of Gag and Gag-Pol polyproteins into structural and enzymatic proteins required for viral replication. It has a similar pharmacophore motif to the other six widely marketed HIV protease inhibitors, most of which are based upon a hydroxyethylamine template. Uniquely, it possesses an aza-peptide motif but maintains many similar pharmacophore elements including lipophilic moieties that presumably bind to S2, S1, S′1, and S′2 positions.