1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0 Posaconazole Intermediate Purity ≥99.0%

Short Description:

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

Appearance: Pale Brown to Off-White Powder

Purity: ≥99.0%

Intermediate of Posaconazole (CAS 171228-49-2) Triazole Antifungal Agent

High Quality, Commercial Production

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Send email to us

Product Detail

Product Tags

Description:

Factory Supply Posaconazole Related Intermediates, Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2

Chemical Properties:

Chemical Name	1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
Synonyms	4-[4-(4-Aminophenyl)piperazin-1-yl]phenol
CAS Number	74853-08-0
CAT Number	RF-PI292
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C16H19N3O
Molecular Weight	269.34
Melting Point	>180℃(dec.)
Density	1.237g/cm3
Shipping Condition	Under Ambient Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	Pale Brown to Off White Powder
Purity	≥99.0%
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Single Impurity	≤0.50%
Total Impurities	≤1.0%
Heavy Metals (as Pb)	≤20ppm
Residual Solvents	Meet the specifications
Test Standard	Enterprise Standard
Usage	Intermediate of Posaconazole (CAS 171228-49-2)

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine (CAS 74853-08-0) is the intermediate of Posaconazole (CAS 171228-49-2). Posaconazole is a triazole antifungal drug marketed in the United States by Schering-Plough under the trade name Noxafil. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14-alpha demethylase.